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周变华,女,1980年2月出生,博士,副教授,山西霍州人。1998-2002本科毕业于山西农业大学,专业为动物医学;2004-2007在山西农业大学攻读硕士学位,专业为临床兽医学,主要从事环境毒理学的研究;2007-2010年在中国农业科学院上海兽医研究所攻读博士学位,专业为兽医药理学,主要从事抗球虫药药物作用分子机理的研究,获中国农业科学院“研究生学术之星”荣誉称号,2010年7月,被授予中国农业科学“优秀毕业生”称号。2010年7月来manbetx万博体育官网工作,主要从事兽医药理学的教学及科研工作,研究方向为兽医药理学,2012年荣获河南科技大学“优秀教师”荣誉称号。主持国家自然科学基金项目1项,参与国家自然科学基金项目4项,另外主持河南科技大学青年科学基金项目1项(编号:2011QN05),博士启动基金项钼1项(编号:09001513)。在《Experimental Parasitology》、《Veterinary Parasitology》、《Parasitology Research》、《Fluoride》、《Environmental Toxicology》及《Toxicology and Industrial Health》等国际SCI收录期刊上发表论文十余篇。获批国家发明专利3项,实用新型专利1项。有3项研究成果已通过河南省科技厅鉴定,达到了国内领先水平。获得河南省自然科学优秀学术论文一等奖2项,二等奖3项。指导1名学生在第26界全国青少年科技创新大赛中荣获“国家一等奖”和“21世纪科技创新奖”。指导3名本科生毕业论文被评为河南科技大学“优秀毕业论文”,主要发表文章如下:

1Bian-hua Zhou, Hong-wei Wang, Zhen-sheng Zhao, Mei Liu, Wen-chao Yan, Jing Zhao, Zhe Zhang, Fei-qun Xue. A novel serine/threonine protein phosphatase type 5 second-generation merozoite ofEimeria tenellais associated with diclazuril-induced apoptosis. Parasitology Research, 2013, 112:1771-1780.

2Bian-hua Zhou, Xiao-jiong Shen, Hong-wei Wang, Tao Li, Fei-qun Xue*. Receptor for activated C kinase ortholog of second-generation merozoite inEimeria tenella: clone, characterization, and diclazuril-induced mRNA expression. Parasitology Research, 2012, 111: 1447-1455.

3Bian-hua Zhou, Hong-wei Wang, Fei-qun Xue, Xiao-yang Wang, Feng-kun Yang, Man-man Ban, Rui-xiang Xin, Cong-cong Wang. Actin-depolymerizing factor of second generation merozoite inEimeria tenella: clone, prokaryotic expression and diclazuril-induced mRNA expression. Parasitology Research, 2010, 106: 571-576.

4Bianhua Zhou, Hongwei Wang, Feiqun Xue, Xiaoyang Wang, Chenzhong Fei, Mi Wang, Tao Zhang, Xiujuan Yao, Peiyi He. Effects of diclazuril on apoptosis and mitochondrial transmembrane potential in second-generation merozoites ofEimeria tenella. Veterinary Parasitology 2010, 168: 217-222.

5Bian-hua Zhou, Hong-wei Wang, Xiao-yang Wang, Li-fang Zhang, Ke-yu Zhang, Fei-qun Xue.Eimeria tenella: Effect of diclazuril treatment on microneme genes expression in second- generation merozoite and pathological changes of caeca in parasitized chickens. Experimental Parasitology, 2010, 125:264-270.

6Bianhua Zhou, Hongwei Wang, Jinming Wang, Jundong Wang. Effects of Malnutrition and Supplemented Nutrition on Specific Immune Parameter Changes Induced by Fluoride in Rabbits. Fluoride 2009, 42(3):216-223.

7Bianhua Zhou, Hongwei Wang, Jinming Wang, Jianhai Zhang, Xiaoyan Yan, Jundong Wang. Effects of malnutrition and supplemented nutrition on nonspecific immune function changes induced by fluoride in rabbits. Fluoride, 2007; 40(3):169-177.

8 Hongwei Wang,Bianhua Zhou, Jinling Cao, Xinli Gu, Chunfang Cao, Jundong Wang. Effects of dietary protein and calcium on thymus apoptosis induced by fluoride in female rats (Wistar Rats). Environmental Toxicology, 2009; 24(3):218-224.

9 Hongwei Wang, Zijun Yang,Bianhua Zhou, Hai Gao, Xiaoyan Yan, Jundong Wang. Fluoride-induced thyroid dysfunction in rats: roles of dietary protein and calcium level. Toxicology and Industrial Health, 2009; 25: 49-57.

10 Jinming Wang, Xiaofang Cheng,Bianhua Zhou, Xiaoyan Yan, Yuxing Guo, Jundong Wang. Effects of protein and calcium on bone metabolism and biomechanical indexes in nutritionally deficient rabbits exposed to high fluoride. Fluoride, 2008; 41(1): 18-27.

11 Hongwei Wang, Yaming Ge,Bianhua Zhou, Jundong Wang. Effect of nutrition and fluoride on thyroid gland in rats. Fluoride, 2007; 40(4): 273-274.

12 Xiaoyan Yan, Wentao Li,Bianhua Zhou, Jinming Wang, Jundong Wang. Effect of supplemented protein and Ca nutrition on fluoride-induced disturbance of rib COL1A1 gene expression in rabbits. Fluoride 2007; 40(2):140-8.

13 Wentao Li, Lifeng Yang,Bianhua Zhou, Xiaoyan Yan, Jundong Wang. Effect of industrial fluoride pollution on COL2A1 gene expression in rib cartilage of Inner Mongolia cashmere goats. Fluoride, 2006; 39(4):285-292.

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